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DriveWays: a method for identifying possibly overlapping driver pathways in cancer
(Nature Research, 2020)
The majority of the previous methods for identifying cancer driver modules output nonoverlapping modules. This assumption is biologically inaccurate as genes can participate in multiple molecular pathways. This is particularly ...
Pythagorean fuzzy VIKOR-based approach for safety risk assessment in mine industry
(Journal of Safety Research, 2019)
Introduction: Underground mining is considered one of the most hazardous industries and is often associated with serious work-related fatalities; this paper addresses job-related hazards and associated risks. Method: A ...
Inferring RBP-mediated regulation in lung squamous cell carcinoma
(Plos One, 2016)
RNA-binding proteins (RBPs) play key roles in post-transcriptional regulation of mRNAs. Dysregulations in RBP-mediated mechanisms have been found to be associated with many steps of cancer initiation and progression. Despite ...
Drosophila as a model for assessing nanopesticide toxicity
(Nanotoxicology, 2020)
One of the fastest-moving fields in today’s world of applied science, nanotechnology allows the control and design of matter on an extremely small scale, so it has now become an integral part of various industries and ...
Sulfur dioxide derivative prevents the prolongation of action potential during the isoproterenol-induced hypertrophy of rat cardiomyocytes
(Anais da Academia Brasileira de Ciências, 2021)
Exogenous SO2 is toxic especially to the pulmonary and cardiovascular system, similar to nitric-oxide, carbon-monoxide, and hydrogen-sulfide. Endogenous SO2 is produced in many cell types. The SO2 content of the rat heart ...
Quaking promotes monocyte differentiation into pro-atherogenic macrophages by controlling pre-mRNA splicing and gene expression
(Nature Communications, 2016)
A hallmark of inflammatory diseases is the excessive recruitment and influx of monocytes to sites of tissue damage and their ensuing differentiation into macrophages. Numerous stimuli are known to induce transcriptional ...
A comparative analysis of breast cancer detection and diagnosis using data visualization and machine learning applications
(Healthcare, 2020)
In the developing world, cancer death is one of the major problems for humankind.
Even though there are many ways to prevent it before happening, some cancer types still do not have
any treatment. One of the most common ...
Cytotoxicity and genotoxicity of cadmium oxide nanoparticles evaluated using in vitro assays
(Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2020)
Cadmium oxide nanoparticles (CdO NPs) are among some of the most studied and industrially used metal oxide NPs. They have been widely used for industrial application, such as paint pigments and electronic devices, and ...
Datasets on mathematical modeling of multi-product multi-stage production to analyze the relationship between production yield, demand, and costs
(Data in Brief, 2019)
The data presented in this article are related to the research article “Optimal procurement and production planning for multi-product multi-stage production under yield uncertainty” (Talay and Özdemir-Akyıldırım, in press) ...
Independent effects on cellular and humoral immune responses underlie genotype-by- genotype interactions between Drosophila and parasitoids
(PLoS Pathogens, 2019)
It is common to find abundant genetic variation in host resistance and parasite infectivity within populations, with the outcome of infection frequently depending on genotype-specific interactions. Underlying these effects ...
