Güncel Gönderiler: DSpace at Antalya Bilim

Toplam kayıt 2170, listelenen: 2061-2080

    • Some surface characteristics of varnished thermowood after weathering 

      Kart, Şaban; Baysal, Ergün; Küçüktüvek, Mustafa; Türkoğlu, Türkay; Toker, Hilmi; Altay, Çağlar; Cibo, Cihan; Peker, Hüseyin (Wood Research, 2019)
      This study was designed to investigate some surface characteristics such as glossiness and surface roughness changes of varnished thermowood after six months of weathering. Thermal modification of Scots pine (Pinus sylvestris ...

    • Deniz suyu kaynaklı ısı pompası ile sıhhi sıcak su temini uygulamasında solar fotovoltaik desteğinin incelenmesi 

      Çengel, Gülsüm; Şenel, Adile; Koçak Soylu, Sezgi; Atmaca, İbrahim (10. Yenilenebilir Enerji Kaynakları Sempozyumu ve Sergisi YEKSEM, 2019)

    • Aynı ekonomik ölçekteki solar termal ve solar fotovoltaik uygulamanın çok yönlü analizi 

      Şenel, Adile; Çengel, Gülsüm; Koçak Soylu, Sezgi; Atmaca, İbrahim (10. Yenilenebilir Enerji Kaynakları Sempozyumu ve Sergisi YEKSEM, 2019)

    • Nanoakışkanlar ve güneş enerjili sıcak su sistemlerinde kullanımı 

      Atmaca, İbrahim; Koçak Soylu, Sezgi; Özdemir, Osman Samet; Asiltürk, Meltem (8. Güneş Enerjisi Sistemleri Sempozyumu ve Sergisi, 2019)
      Nanoakışkanlar en genel tanımıyla; nanometrik boyuttaki (1-100 nm) katı partiküllerin bir temel akışkan içerisinde dağıtılması ile oluşturulan akışkanlardır. Böyle bir yapı oluşturmaktaki amaç, ısıl iletkenliği temel ...

    • MEXCOwalk: mutual exclusion and coverage based random walk to identify cancer modules 

      Ahmed, Rafsan; Baali, Ilyes; Erten, Cesim; Hoxha, Evis; Kazan, Hilal (Bioinformatics, 2019)
      Motivation: Genomic analyses from large cancer cohorts have revealed the mutational heterogeneity problem which hinders the identification of driver genes based only on mutation profiles. One way to tackle this problem ...

    • MITF-MIR211 axis is a novel autophagy amplifier system during cellular stress 

      Öztürk, Deniz Gülfem; Koçak, Muhammed; Akçay, Arzu; Kınoğlu, Kubilay; Kara, Erdoğan; Büyük, Yalçın; Kazan, Hilal; Gözüaçık, Devrim (Autophagy, 2019)
      Macroautophagy (autophagy) is an evolutionarily conserved recycling and stress response mechanism. Active at basal levels in eukaryotes, autophagy is upregulated under stress providing cells with building blocks such as ...

    • RBPSponge: genome-wide identification of lncRNAs that sponge RBPs 

      HafezQorani, Saber; Houdjedj, Aissa; Arıcı, Mehmet; Said, Abdesselam; Kazan, Hilal (Bioinformatics, 2019)
      Long non-coding RNAs (lncRNAs) can act as molecular sponge or decoys for an RNA-binding protein (RBP) through their RBP-binding sites, thereby modulating the expression of all target genes of the corresponding RBP of ...

    • A translational repression complex in developing mammalian neural stem cells that regulates neuronal specification 

      Zahr, Siraj K.; Yang, Guang; Kazan, Hilal; Borrett, Michael J.; Voronova, Anastassia; Kaplan, David R.; Miller, Freda D. (Neuron, 2018)
      The mechanisms instructing genesis of neuronal sub-types from mammalian neural precursors are not well understood. To address this issue, we have characterized the transcriptional landscape of radial glial precursors (RPs) ...

    • Predicting clinical outcomes in neuroblastoma with genomic data integration 

      Baali, Ilyes; Acar, D. Alp Emre; Aderinwale, Tunde W.; HafezQorani, Saber; Kazan, Hilal (Biology Direct, 2018)
      Background: Neuroblastoma is a heterogeneous disease with diverse clinical outcomes. Current risk group models require improvement as patients within the same risk group can still show variable prognosis. Recently collected ...

    • Inferring RBP-mediated regulation in lung squamous cell carcinoma 

      Lafzi, Atefeh; Kazan, Hilal (Plos One, 2016)
      RNA-binding proteins (RBPs) play key roles in post-transcriptional regulation of mRNAs. Dysregulations in RBP-mediated mechanisms have been found to be associated with many steps of cancer initiation and progression. Despite ...

    • A comprehensive database of high-throughput sequencing-based RNA secondary structure probing data (structure surfer) 

      Berkowitz, Nathan D.; Silverman, Ian M.; Childress, Daniel M.; Kazan, Hilal; Wang, Li-San; Gregory, Brian D. (BMC Bioinformatics, 2016)
      Background: RNA molecules fold into complex three-dimensional shapes, guided by the pattern of hydrogen bonding between nucleotides. This pattern of base pairing, known as RNA secondary structure, is critical to their ...

    • Chemogenomics and orthology‐based design of antibiotic combination therapies 

      Chandrasekaran, Sriram; Çokol-Çakmak, Melike; Şahin, Nil; Yılancıoğlu, Kaan; Kazan, Hilal; Collins, James J.; Çokol, Murat (Molecular Systems Biology, 2016)
      Combination antibiotic therapies are being increasingly used in the clinic to enhance potency and counter drug resistance. However, the large search space of candidate drugs and dosage regimes makes the identification ...

    • Quaking promotes monocyte differentiation into pro-atherogenic macrophages by controlling pre-mRNA splicing and gene expression 

      Bruin, Ruben G. de; Shiue, Lily; Prins, Jurrien; Boer, Hetty C. de; Singh, Anjana; Fagg, W. Samuel; Gils, Janine M. vans; Duijs, Jacques M. G. J.; Katzman, Sol; Kraaijeveld, Adriaan O.; Bohringer, Stefan; Leung, Wai Y.; Kielbasa, Szymon M.; Donahue, John P.; Zande, Patrick H. J. van der; Sijbom, Rick; Alem, Carla M. A. van; Bot, Ilze; Kooten, Cees van; Jukema, J. Wouter; Van Esch, Hilde; Rabelink, Ton J.; Kazan, Hilal; Biessen, Erik A. L.; Ares, Manuel; Zonneveld, Anton Jan van; Veer, Eric P. van der (Nature Communications, 2016)
      A hallmark of inflammatory diseases is the excessive recruitment and influx of monocytes to sites of tissue damage and their ensuing differentiation into macrophages. Numerous stimuli are known to induce transcriptional ...

    • Modeling gene regulation in liver hepatocellular carcinoma with random forests 

      Kazan, Hilal (BioMed Research International, 2016)
      Liver hepatocellular carcinoma (HCC) remains a leading cause of cancer-related death. Poor understanding of the mechanisms underlying HCC prevents early detection and leads to high mortality. We developed a random forest ...

    • Modeling the combined effect of RNA-binding proteins and microRNAs in post-transcriptional regulation 

      HafezQorani, Saber; Lafzi, Atefeh; Bruin, Ruben G. de; Zonneveld, Anton Jan van; Veer, Eric P. van der; Aydın Son, Yeşim; Kazan, Hilal (Nucleic Acids Research, 2016)
      Recent studies show that RNA-binding proteins (RBPs) and microRNAs (miRNAs) function in coordination with each other to control post-transcriptional regulation (PTR). Despite this, the majority of research to date has ...

    • JBASE: Joint Bayesian Analysis of Subphenotypes and Epistasis 

      Kazan, Hilal; Çolak, Recep; Kim, TaeHyung; Oh, Yoomi; Cruz, Miguel; Valladares Salgado, Adan; Peralta, Jesus; Escobedo, Jorge; Parra, Esteban J.; Kim, Philip M.; Goldenberg, Anna (Bioinformatics, 2015)
      Motivation: Rapid advances in genotyping and genome-wide association studies have enabled the discovery of many new genotype–phenotype associations at the resolution of individual markers. However, these associations explain ...

    • Target-independent prediction of drug synergies using only drug lipophilicity 

      Kazan, Hilal; Yılancıoğlu, Kaan; Weinstein, Zohar B.; Meydan, Cem; Akhmetov, Azat; Toprak, Işıl; Durmaz, Arda; Iossifov, Ivan; Roth, Frederick P.; Çokol, Murat (Journal of Chemical Information and Modeling, 2014)
      Physicochemical properties of compounds have been instrumental in selecting lead compounds with increased drug-likeness. However, the relationship between physicochemical properties of constituent drugs and the tendency ...

    • Turizm sektörü girişimcilerinin yatırım kararlarını etkileyen iç ve dış etkenlerin belirlenmesi 

      Başer, Gözdegül; Mutlu, Eda Evla (International West Asia Congress of Tourism Research, 2018)
      Bu araştırmanın amacı, Antalya Bölgesi’ndeki turizm yatırımcılarının, yatırım yapma süreçlerinde yatırım kararlarını nasıl aldıkları, hangi içsel ve dışsal nedenlerle hareket ettiklerini belirlemektir. Bu amaç doğrultusunda, ...

    • Corporate website content related to disability in the top 50 fortune firms in Turkey 

      Nazlı, Murat; Mutlu, Eda Evla (International Journal of Management Economics and Business, 2018)
      As a result of worldwide increased awareness in disability, organizations in Turkey are also assumed to reconsider their values, norms and behaviors accordingly. Considering the intention of maintaining legitimacy in ...

    • Exploring the performance of hotels’ websites for guests with disabilities: a content analysis approach 

      Nazlı, Murat; Mutlu, Eda Evla (Business & Management Studies: An International Journal, 2018)
      The globally rising awareness about the social inclusion of individuals with disabilities also influences the tourism and hospitality industry in Turkey. This exploratory research focuses on the disability related content ...